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Zhe Zhang Selected Research

Polo-Like Kinase 1

12/2017Comprehensive analysis of differentially expressed genes associated with PLK1 in bladder cancer.
1/2017Targeted inhibition of Polo-like kinase 1 by a novel small-molecule inhibitor induces mitotic catastrophe and apoptosis in human bladder cancer cells.
1/2015Inhibition of Plk1 represses androgen signaling pathway in castration-resistant prostate cancer.
11/2014Plk1 inhibition enhances the efficacy of androgen signaling blockade in castration-resistant prostate cancer.
10/2013High expression of polo-like kinase 1 is associated with the metastasis and recurrence in urothelial carcinoma of bladder.
6/2013Polo-like kinase 1 is overexpressed in renal cancer and participates in the proliferation and invasion of renal cancer cells.

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Zhe Zhang Research Topics

Disease

286Neoplasms (Cancer)
11/2022 - 10/2004
60Neoplasm Metastasis (Metastasis)
12/2022 - 09/2005
55Breast Neoplasms (Breast Cancer)
09/2022 - 12/2005
44Nasopharyngeal Carcinoma
01/2022 - 12/2005
43Inflammation (Inflammations)
10/2022 - 09/2005
34Urinary Bladder Neoplasms (Bladder Cancer)
03/2022 - 07/2012
27Infections
06/2022 - 08/2003
27Carcinogenesis
01/2022 - 11/2010
25Stomach Neoplasms (Stomach Cancer)
01/2022 - 12/2013
23Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
04/2022 - 01/2014
23Carcinoma (Carcinomatosis)
01/2022 - 08/2009
21Lung Neoplasms (Lung Cancer)
04/2022 - 04/2010
19Glioma (Gliomas)
09/2022 - 09/2003
17Colorectal Neoplasms (Colorectal Cancer)
01/2022 - 01/2014
16Hypoxia (Hypoxemia)
08/2022 - 07/2009
16Prostatic Neoplasms (Prostate Cancer)
03/2020 - 03/2007
14Renal Cell Carcinoma (Grawitz Tumor)
01/2022 - 01/2012
12Ischemic Stroke
08/2022 - 01/2018
12Fibrosis (Cirrhosis)
08/2022 - 01/2010
12Mitochondrial Diseases (Mitochondrial Disease)
12/2021 - 03/2010
11Adenocarcinoma of Lung
03/2022 - 05/2012
10Wounds and Injuries (Trauma)
12/2022 - 11/2009
10Stroke (Strokes)
10/2022 - 08/2012
10Thrombosis (Thrombus)
02/2022 - 04/2008
10Pain (Aches)
01/2022 - 09/2006
10Body Weight (Weight, Body)
01/2022 - 05/2012
9Insulin Resistance
12/2022 - 04/2012
9Reperfusion Injury
01/2021 - 07/2009
8Ischemia
08/2022 - 11/2009
8COVID-19
05/2022 - 01/2020
8Cardiovascular Diseases (Cardiovascular Disease)
01/2022 - 02/2010
8Squamous Cell Carcinoma of Head and Neck
01/2022 - 08/2009
8Hepatocellular Carcinoma (Hepatoma)
01/2020 - 08/2009
8Leukemia
06/2019 - 10/2013
8Systemic Lupus Erythematosus (Libman-Sacks Disease)
11/2018 - 01/2014
7Colonic Neoplasms (Colon Cancer)
01/2022 - 11/2014
7Hemorrhage
01/2022 - 04/2006
7Constipation
12/2021 - 04/2019
7Hypertension (High Blood Pressure)
11/2021 - 09/2006
7Myocardial Ischemia (Ischemic Heart Diseases)
04/2020 - 11/2009
7Endometriosis
01/2020 - 03/2014
7Chronic Kidney Failure (Chronic Renal Failure)
01/2019 - 10/2015
6Obesity
12/2022 - 12/2011
6Triple Negative Breast Neoplasms
09/2022 - 08/2009
6Myocardial Infarction
08/2022 - 03/2014
6Liver Neoplasms (Liver Cancer)
01/2022 - 01/2016
6Atherosclerosis
10/2021 - 02/2002
6Lymphatic Metastasis
09/2021 - 06/2007
6Virus Diseases (Viral Diseases)
08/2021 - 12/2012

Drug/Important Bio-Agent (IBA)

87Proteins (Proteins, Gene)FDA Link
09/2022 - 09/2008
63Biomarkers (Surrogate Marker)IBA
12/2022 - 01/2007
45Pharmaceutical PreparationsIBA
06/2022 - 01/2007
33Messenger RNA (mRNA)IBA
01/2022 - 12/2005
33MicroRNAs (MicroRNA)IBA
12/2021 - 01/2013
24Biological ProductsIBA
01/2022 - 12/2005
23DNA (Deoxyribonucleic Acid)IBA
01/2022 - 06/2006
18Small Interfering RNA (siRNA)IBA
11/2022 - 12/2005
18CytokinesIBA
04/2022 - 11/2006
17LipidsIBA
10/2022 - 12/2012
17Long Noncoding RNAIBA
03/2022 - 06/2017
16Glucose (Dextrose)FDA LinkGeneric
12/2022 - 12/2011
16RNA (Ribonucleic Acid)IBA
03/2022 - 10/2004
16EnzymesIBA
11/2021 - 12/2005
14Hormones (Hormone)IBA
12/2022 - 10/2011
14VaccinesIBA
06/2022 - 10/2004
14AntigensIBA
11/2021 - 06/2003
13Doxorubicin (Adriamycin)FDA LinkGeneric
10/2020 - 02/2010
12Therapeutic UsesIBA
11/2022 - 06/2019
12CollagenIBA
08/2022 - 09/2010
12Transcription Factors (Transcription Factor)IBA
01/2022 - 12/2008
11Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2021 - 12/2009
10Interleukin-6 (Interleukin 6)IBA
08/2022 - 06/2009
9LigandsIBA
05/2022 - 06/2007
9AntibodiesIBA
01/2022 - 12/2012
9Estrogen ReceptorsIBA
01/2022 - 06/2010
9Phosphotransferases (Kinase)IBA
01/2019 - 09/2014
8ErbB Receptors (EGF Receptor)IBA
04/2022 - 06/2010
8CateninsIBA
01/2022 - 12/2011
8AntioxidantsIBA
01/2022 - 07/2009
8Indicators and Reagents (Reagents)IBA
06/2021 - 08/2009
8Antineoplastic Agents (Antineoplastics)IBA
12/2020 - 01/2006
8Epidermal Growth Factor (EGF)IBA
01/2020 - 06/2010
7Monoclonal AntibodiesIBA
01/2021 - 05/2008
6Capsules (Microcapsules)IBA
06/2022 - 12/2008
6Tyrosine Kinase InhibitorsIBA
04/2022 - 01/2019
6Peptides (Polypeptides)IBA
02/2022 - 06/2017
6Oxygen (Dioxygen)IBA
01/2022 - 01/2002
6Competitive Endogenous RNAIBA
01/2022 - 01/2018
6Reactive Oxygen Species (Oxygen Radicals)IBA
01/2022 - 01/2013
6InterleukinsIBA
12/2021 - 03/2016
6human ERBB2 proteinIBA
07/2021 - 09/2014
6AlbuminsIBA
01/2021 - 11/2006
6CholesterolIBA
01/2021 - 05/2013

Therapy/Procedure

131Therapeutics
04/2022 - 08/2003
41Drug Therapy (Chemotherapy)
05/2022 - 08/2009
15Radiotherapy
01/2022 - 03/2007
13Immunotherapy
01/2022 - 10/2004
13Palliative Care (Palliative Therapy)
03/2021 - 05/2014
10Chinese Traditional Medicine (Traditional Chinese Medicine)
01/2022 - 08/2014
6Stents
01/2021 - 09/2013